心脏记忆的节律失常效应
Sami Viskin1, Ehud Chorin1, Arie Lorin Schwartz1
1Department of Cardiology, Tel Aviv Sourasky Medical Center and Sackler School of Medicine, Tel Aviv University, Israel (S.V., E.C., A.L.S., R.R.).
Circulation
|October 10, 2022
概括
心脏记忆,一种心电图学现象,可以增加敏感个体患危险心律失常的风险. 这次审查突出了其潜在的心律失常效应,以前没有受到重视.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
背景情况:
- 心脏记忆描述了一个短暂的心电图学现象,在QRS复杂形态恢复到基线后,T波逐渐正常化.
- 这种现象通常被认为是无辜的发现.
- 然而,它涉及到心脏再极化中的改变.
研究的目的:
- 审查心脏记忆的低估的节律失常性潜力.
- 突出心脏记忆与特定患者群体内心室节律失常的发展之间的联系.
主要方法:
- 审查有关心脏记忆及其电生理学基础的现有文献.
- 分析心脏记忆期间改变反极化对心脏电生理学的影响.
主要成果:
- 心脏记忆与减少复极化电流有关,导致左心室复极化梯度增加.
- 在已经存在延长QT间隔的患者中,心脏记忆可以导致危险的心室失律,包括torsades de pointes.
- 这些心律失常效应尚未得到广泛认可.
结论:
- 心脏记忆不仅仅是一个无辜的心电图好奇心.
- 它在患有 QT 间隔延长的患者中引发心室节律失常的风险很大.
- 需要进一步的临床意识和调查.
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