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Updated: Aug 26, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
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通过低氧诱导因子1α激活γ-环球蛋白表达

Ruopeng Feng1, Thiyagaraj Mayuranathan1, Peng Huang2

  • 1Department of Hematology, St Jude Children's Research Hospital, Memphis, TN, USA.

Nature
|October 12, 2022
PubMed
概括

研究人员通过向VHL-HIF1α途径发现了一种新方法来促进胎儿红细胞 (RBC) 的血红蛋白 (HbF) 生产. 这一发现为治疗状细胞病和β-血症等血液疾病提供了潜在的治疗策略.

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