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Updated: Aug 25, 2025

Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum
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Author Spotlight: THP-1 Macrophage Response to LPS/ATP — Unveiling the Pyroptosis, Apoptosis, and Necroptosis Spectrum

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一种细菌脂酸酶通过劫持无处不在物质来抑制宿主灭

Qiyao Chai1, Shanshan Yu2, Yanzhao Zhong1,3

  • 1CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China.

Science (New York, N.Y.)
|October 13, 2022
PubMed
概括

结核菌使用PtpB来通过脱化细胞膜来抑制宿主炎症酶 - 炎症酶路径,从而逃避免疫反应. 破坏PtpB的活性会增强免疫力,并减少病原体的存活率.

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