博格是巨大的遗传元素具有扩大代谢能力的潜力
Basem Al-Shayeb1,2, Marie C Schoelmerich1, Jacob West-Roberts3
1Innovative Genomics Institute, University of California, Berkeley, CA, USA.
Nature
|October 19, 2022
概括
研究人员在甲氧化环境中发现了大量的新型DNA序列, 这些元素可能通过为古生物提供新的基因来影响温室气体排放.
科学领域:
- 微生物学
- 基因组学
- 环境科学
背景情况:
- 无氧甲氧化对于调节温室气体排放至关重要.
- 影响甲氧化的微生物的因素尚不清楚.
研究的目的:
- 研究各种生态系统中涉及甲生产和氧化的微生物的遗传组成.
- 在这些环境中发现的新型DNA序列.
主要方法:
- 来自地下水,沉积物和湿地土壤的基因组测序和DNA分析.
- 遗传学分析和基因序列比较.
- 识别和描述大型的染色体外DNA元素.
主要成果:
- 发现了异常庞大且多样化的DNA序列, 命名为"博格",
- 四个完整的博格线性基因组被测序, 显示出独特的基因组组织和并列重复.
- 博格似乎是高度分离的古老的染色体外元素,有证据表明基因同化来自甲氧化甲.
- 发现至少有19种不同的博格类型与Methanoperedens spp共存. 在四个生态系统中.
- 博格为甲氧化的古生物提供了氧化还原反应和能量保存的基因.
结论:
- 博格代表了一类具有独特进化历史的古老染色体外元素.
- 这些元素可能在甲氧化古生物的新陈代谢中发挥着重要的,以前未知的作用.
- 博格和宿主古生物之间的相互作用可能对理解和调节温室气体排放产生影响.
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