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Updated: Aug 24, 2025

Hybrid De Novo Genome Assembly for the Generation of Complete Genomes of Urinary Bacteria using Short- and Long-read Sequencing Technologies
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高质量的双胞胎人类基因组的半自动组装

Erich D Jarvis1,2, Giulio Formenti3, Arang Rhie4

  • 1Vertebrate Genome Laboratory, The Rockefeller University, New York, NY, USA. ejarvis@rockefeller.edu.

Nature
|October 19, 2022
PubMed
概括

这项研究开发了一种新方法来创建精确的双体人体基因组组. 该方法使用长读数和亲子数据来构建代表人类遗传多样性的泛基因组参考.

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Automated Robotic Liquid Handling Assembly of Modular DNA Devices

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相关概念视频

Genome Annotation and Assembly03:36

Genome Annotation and Assembly

The genome refers to all of the genetic material in an organism. It can range from a few million base pairs in microbial cells to several billion base pairs in many eukaryotic organisms. Genome assembly refers to the process of taking the DNA sequencing data and putting it all back together in a correct order to create a close representation of the original genome. This is followed by the identification of functional elements on the newly assembled genome, a process called genome annotation.
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