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Updated: Aug 23, 2025

Experimental Melanoma Immunotherapy Model Using Tumor Vaccination with a Hematopoietic Cytokine
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系统性疫苗接种诱导CD8+T细胞并重塑瘤微环境

Faezzah Baharom1, Ramiro A Ramirez-Valdez2, Ahad Khalilnezhad3

  • 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA; Genentech, South San Francisco, CA 94080, USA.

Cell
|October 27, 2022
PubMed
概括

通过使用纳米粒子疫苗进行静脉注射,通过减少抑制性骨髓细胞,有效地回归瘤. 这种方法增强了抗瘤T细胞免疫力,并重塑瘤微环境 (TME) 以改善癌症免疫治疗.

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