Jove
Visualize
联系我们

相关概念视频

Olfaction01:25

Olfaction

44.8K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
44.8K
Association Areas of the Cortex01:21

Association Areas of the Cortex

5.9K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
5.9K
Motor and Sensory Areas of the Cortex01:14

Motor and Sensory Areas of the Cortex

4.3K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
4.3K
Somatosensory, Motor, and Association Cortex01:24

Somatosensory, Motor, and Association Cortex

742
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
742
Role of Hippocampus in Memory01:19

Role of Hippocampus in Memory

470
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
470
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

556
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
556

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Subicular Plateaus Signal Reward Locations during Goal-Directed Behavior.

bioRxiv : the preprint server for biology·2026
Same author

Behavioral timescale synaptic plasticity: properties, elements and functions.

Nature neuroscience·2026
Same author

Learning-dependent feedback by OLM interneurons shapes CA1 representations.

bioRxiv : the preprint server for biology·2026
Same author

Formation of an expanding memory representation in the hippocampus.

Nature neuroscience·2025
Same author

An unsuspected physiological role for mGluRIII glutamate receptors in hippocampal area CA1.

bioRxiv : the preprint server for biology·2025
Same author

Mechanisms of experience-dependent place-cell referencing in hippocampal area CA1.

Nature neuroscience·2025
Same journal

Inside the new political screening that's stalling NIH grants.

Nature·2026
Same journal

Europe's record heatwave: does the continent have a new climate?

Nature·2026
Same journal

Daily briefing: Humans and great apes giggle in the same rhythms.

Nature·2026
Same journal

The surprising career parallels between footballers and researchers.

Nature·2026
Same journal

I study World Cup penalty shoot-outs: they say a lot about the psychology of performance under pressure.

Nature·2026
Same journal

CRISPR's next act: the companies editing the epigenome to treat disease.

Nature·2026
查看所有相关文章
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关实验视频

Updated: Aug 23, 2025

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

12.7K

脑内皮层指导CA1表现的与学习相关的变化

Christine Grienberger1,2, Jeffrey C Magee3

  • 1Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX, USA.

Nature
|November 3, 2022
PubMed
概括
此摘要是机器生成的。

这项研究揭示了大脑如何通过增强海马活动来学习位置. 这一过程依赖于由内皮层3驱动的突触可塑性, 这对于适应性行为至关重要.

更多相关视频

Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex
09:45

Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex

Published on: March 28, 2012

15.7K
Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity
11:56

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity

Published on: November 11, 2017

15.6K

相关实验视频

Last Updated: Aug 23, 2025

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording
14:27

Investigating Long-term Synaptic Plasticity in Interlamellar Hippocampus CA1 by Electrophysiological Field Recording

Published on: August 11, 2019

12.7K
Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex
09:45

Preparation of Parasagittal Slices for the Investigation of Dorsal-ventral Organization of the Rodent Medial Entorhinal Cortex

Published on: March 28, 2012

15.7K
Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity
11:56

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity

Published on: November 11, 2017

15.6K

科学领域:

  • 神经科学
  • 突触可塑性
  • 学习和记忆

背景情况:

  • 适应性行为是由与学习相关的大脑活动的变化驱动的.
  • 在动物中,奖励位置的海马体过度表现对于学习至关重要.
  • 这些海马变化的确切机制尚不清楚.

研究的目的:

  • 调查与学习相关的变化,特别是奖励位置的过度代表,发生在海马体.
  • 确定神经回路和参与学习过程的可塑性机制.

主要方法:

  • 在线跑步机上学习奖励位置的小鼠中记录了海马CA1群体活动.
  • 利用生理和药理证据来评估行为时间尺度突触可塑性 (BTSP) 的作用.
  • 采用内腔皮层3 (EC3) 的光遗传抑制来研究其在指导可塑性的作用.

主要成果:

  • 发现适应性海马过度表现需要BTSP.
  • 抑制EC3活动显著降低了CA1的过度表现.
  • EC3神经元表现出一种可以指示BTSP的活动模式,

结论:

  • 与海马学习相关的变化是由EC3指导的突触可塑性介导的.
  • 似乎是针对行为相关的环境特征, 如奖励线索.
  • 这项研究阐明了大脑如何编码和学习环境信息的新机制.