高血压的治疗:一篇综述
Robert M Carey1, Andrew E Moran2, Paul K Whelton3
1Division of Endocrinology and Metabolism, Department of Medicine, University of Virginia Health System, Charlottesville.
JAMA
|November 8, 2022
概括
全球超过10亿成年人患有高血压. 改变生活方式和药物治疗是控制血压和降低心血管疾病风险的关键.
科学领域:
- 心脏病学和公共卫生
背景情况:
- 高血压 (高血压) 影响全球超过10亿成年人,增加心血管疾病 (CVD) 的风险,如心脏病发作和中风.
- 有效的血压管理对于降低心血管疾病发病率和死亡率至关重要.
研究的目的:
- 概述高血压管理的当前指导方针,强调生活方式修改和药理疗法.
- 为了强调血压控制在预防心血管疾病事件中的重要性.
主要方法:
- 对已建立的高血压第一线治疗方法的审查.
- 讨论生活方式的改变,包括饮食,运动和饮酒.
- 推的药理学药剂和BP目标的概述.
主要成果:
- 改变生活方式是高血压管理的基石,是药物治疗的补充.
- 第一线药物包括提亚齐德利尿剂,ACE抑制剂/ARB和通道阻塞剂.
- 达到血压目标可显著降低心血管疾病风险,每小时10毫米的SBP降低可使心血管疾病发生风险降低20-30%.
结论:
- 高血压是全球主要的健康挑战,需要全面的管理策略.
- 改变生活方式和基于证据的药物治疗的结合对于有效的血压控制至关重要.
- 尽管已证明有好处,但美国很大一部分高血压患者仍未得到足够的治疗.
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