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Updated: Aug 21, 2025

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
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Published on: August 16, 2019

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针对与α- 肌肉素驱动免疫治疗相关的T细胞

Margaret L Axelrod1, Wouter C Meijers1,2,3, Elles M Screever1,2,3

  • 1Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

Nature
|November 17, 2022
PubMed
概括

免疫检查点抑制剂 (ICI) 可能导致严重的心肌炎. 这项研究确定了CD8+T细胞和α- 肌肉素是ICI相关心肌炎的关键参与者,提供了新的治疗点.

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