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通过获得大型活性场电场,β-乳酸酶对抗抗生素

Zhe Ji1, Steven G Boxer1

  • 1Department of Chemistry, Stanford University, Stanford, California 94305, United States.

Journal of the American Chemical Society
|November 18, 2022
PubMed
概括

酶活性部位的电场通过改变共价键反应性来驱动抗生素耐药性的演变. 了解这些领域有助于设计新药来克服抗药性.

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