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中国的健康老龄化之路:北京大学-兰塞特委员会

Xinxin Chen1, John Giles2, Yao Yao3

  • 1Institute of Social Science Survey, Peking University, Beijing, China.

Lancet (London, England)
|November 24, 2022
PubMed
概括

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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
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