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Updated: Aug 19, 2025

CRISPR/Cas9-mediated Targeted Integration In Vivo Using a Homology-mediated End Joining-based Strategy
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Published on: March 12, 2018

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全球CRISPRRNA导向转子体整合复合物的结构

Jung-Un Park1, Amy Wei-Lun Tsai1, Alexandrea N Rizo1

  • 1Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.

Nature
|November 28, 2022
PubMed
概括

研究人员确定了Scytonema hofmannii与CRISPR相关的转子体 (CAST) 的结构. 这揭示了CAST元素如何整合DNA,为精确的基因组编辑应用提供了洞察力.

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