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Phospho Flow Cytometry with Fluorescent Cell Barcoding for Single Cell Signaling Analysis and Biomarker Discovery
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中下质谱揭示了C G类蛋白结合受体中的活性修饰酸化条形码

Ashley N Ives1, Henry A Dunn2,3,4, Hamid Samareh Afsari5

  • 1Department of Chemistry, Northwestern University, Evanston, Illinois 60208 United States.

Journal of the American Chemical Society
|December 8, 2022
PubMed
概括

这项研究引入了一种新的蛋白质学方法,用于精确测量G蛋白结合受体 (GPCR) 酸化. 这种技术量化了受体化状态,对于理解GPCR信号和开发新疗法至关重要.

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