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通过特定结构的纳米体在体外和活细胞中识别DNA G-四重复

Silvia Galli1,2, Larry Melidis1,2, Sean M Flynn1

  • 1Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, U.K.

Journal of the American Chemical Society
|December 9, 2022
PubMed
概括

研究人员开发了SG4,用于检测DNA中的G四重复体 (G4s) 的纳米体探针. 这种新工具克服了以前的探测器的局限性,使细胞内G4成像和活细胞映射成为可能.

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