相关实验视频
Updated: Aug 10, 2026

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Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
二维超声波组织表征:反射散射功率,内心壁运动,以及它们对正常,缺血和心肌梗塞的相位关系
P J Fitzgerald1, M D McDaniel, E L Rolett
1Cardiology Section, Dartmouth-Hitchcock Medical Center, Dartmouth Medical School, Hanover, NH.
Circulation
|October 1, 1987
概括
超声波反射散射功率和相位差异在犬类心肌中在缺血和心脏病发作期间可预见地发生变化. 这些变化反映了组织变化和壁的运动,为心肌损伤评估提供了洞察力.
科学领域:
- 心血管超声波是什么意思
- 肌肉心脏成像成像 肌肉心脏成像
- 生物医学工程 生物医学工程
背景情况:
- 非侵入性评估心肌活力对于诊断和管理心脏病至关重要.
- 超声波能量反射特性可以潜在地区分健康,缺血和心脏病发作的心脏组织.
研究的目的:
- 为了研究在诱导性缺血和心脏病发作期间从狗心肌中反射的超声波能量 (反射功率和相位) 的变化.
- 为了将这些超声波参数与内心壁运动和左心室压力相关联.
主要方法:
- 使用2D超声波扫描仪在接受控制冠状动脉封闭 (2-5小时) 或临时紧/再输液的开胸狗身上.
- 测量了循环反向散射功率 (BSP) 和内心壁运动 (EWM),BSP和左心室压力 (LVP) 之间的相差.
主要成果:
- 周期性BSP在缺血期间显著下降,并在发作期间部分恢复.
- 在缺血和心脏病发作期间,EWM和BSP之间的相位差异逐渐增加.
- 重灌使BSP和相位差异正常化.
- 在心脏病发作5小时后,动力障碍对总相差的贡献为46%,反向散射功率为54%.
结论:
- 超声波反射散射功率和相位变化是心肌缺血和心脏梗塞的敏感指标.
- 这些参数,特别是它们与墙壁运动的相位关系,可以帮助区分正常,缺血和心肌梗塞.
- 这些发现表明,基于超声波评估心肌损伤和生存能力的可能性很大.
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