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Updated: Aug 16, 2025

A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain
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A "Plug-And-Display" Nanoparticle Vaccine Platform Based on Outer Membrane Vesicles Displaying SARS-CoV-2 Receptor-Binding Domain

Published on: July 25, 2022

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印记的SARS-CoV-2 幽默免疫诱导了融合的欧米克朗 RBD 进化

Yunlong Cao1,2, Fanchong Jian3,4, Jing Wang3,5

  • 1Biomedical Pioneering Innovation Center (BIOPIC), Peking University, Beijing, P. R. China. yunlongcao@pku.edu.cn.

Nature
|December 19, 2022
PubMed
概括

在受体结合域 (RBD) 中,Omicron变异迅速演变,避开抗体和疫苗. 这种由免疫印记驱动的融合进化对目前针对SARS-CoV-2的免疫策略构成威胁.

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