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Updated: Aug 13, 2025

Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation
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Three and Four-Dimensional Visualization and Analysis Approaches to Study Vertebrate Axial Elongation and Segmentation

Published on: February 28, 2021

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控制器官对称性破裂揭示了人类轴延伸的可刺激系统

Giridhar M Anand1, Heitor C Megale1, Sean H Murphy1

  • 1Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA; Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.

Cell
|January 19, 2023
PubMed
概括

研究人员开发了一种生物工程框架,以创建模仿早期胚胎发育的人类器官. 该系统揭示了WNT/FGF信号和WNT抑制剂如何控制稳定的轴延长和尾芽形成.

关键词:
轴延长生物工程人类干细胞模型可复制的统计推断

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