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Updated: Aug 13, 2025

Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex
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Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex

Published on: February 25, 2022

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全光生理学解决了行为时间尺度可塑性的突触基础

Linlin Z Fan1, Doo Kyung Kim1, Joshua H Jennings1

  • 1Department of Bioengineering, Stanford University, Stanford, CA, USA.

Cell
|January 20, 2023
PubMed
概括

研究人员通过观察小鼠学习过程中的突触变化, 发现海马是如何存储信息的. 这项研究详细介绍了行为时间尺度可塑性的神经机制.

关键词:
全光电生理学激发性海马的行为时间尺度可塑性进行成像视觉遗传学位置单元突触可塑性

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相关概念视频

Long-term Potentiation01:25

Long-term Potentiation

Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
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