在2021-2022年家庭传播流感A病毒
在PubMed上查看摘要
概括
此摘要是机器生成的。与流行病前的年份相比,2021-2022年季节流感A ((H3N2) 的家庭传播显著增加. 这种流感风险的增加表明免疫力下降可能是一个因素.
科学领域
- 流行病学
- 病毒学
- 公共卫生
背景情况
- 在COVID-19大流行期间,全球流感病毒感染率有所下降.
- 自然免疫力下降和病毒抗原变化可能会增加对流感的敏感性.
- 在2021-2022赛季,流感传播的可能性有所增加.
研究的目的
- 在家庭接触者中比较流感病毒感染的风险.
- 评估2021-2022赛季和美国疫情前赛季的传播情况.
主要方法
- 美国家庭流感传播的前性研究 (2017-2020年和2021-2022年).
- 作为主要病例的实验室确诊流感A ((H3N2) 的家庭.
- 家庭接触者每天进行分子检测和5-10天的症状监测.
主要成果
- 在疫情前的季节,20.1%的家庭接触者被感染,而在2021-2022年,这一比例为50.0%.
- 与大流行前的季节相比,2021-2022年,调整后的流感A ((H3N2) 感染相对风险为2.31.
- 在美国5个州的队列中观察到增加的风险.
结论
- 在2021-2022年,流感A ((H3N2) 的家庭传播率明显高于疫情前的季节.
- 需要进一步研究以阐明这种传播增加的原因.
- 这些发现突显了流感流行病学后的潜在变化.
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