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Updated: Aug 11, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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Published on: September 20, 2018

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修改后的H2A-H2B的回收提供了对染色质状态的短期记忆

Valentin Flury1, Nazaret Reverón-Gómez1, Nicolas Alcaraz1

  • 1Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, 2200 Copenhagen, Denmark; Biotech Research and Innovation Centre, University of Copenhagen, 2200 Copenhagen, Denmark.

Cell
|February 7, 2023
PubMed
概括

在DNA复制过程中,父母的H2A-H2B基因组修饰被准确地循环,确保了表观遗传. 这一过程指导着色素状态的恢复,保持基因组调节和细胞身份.

关键词:
进行DNA复制H2A 其他在H2A.Z在H2B中染色体基因组 PTM 交叉通话基因子的回收多种翻译后的修改无处不在

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