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Updated: Aug 11, 2025

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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Published on: March 2, 2014

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一个E1-E2融合蛋白在细菌中启动抗病毒免疫信号

Hannah E Ledvina1, Qiaozhen Ye2, Yajie Gu2

  • 1Department of Biochemistry, University of Colorado Boulder, Boulder, CO, USA.

Nature
|February 9, 2023
PubMed
概括

细菌使用类似于Ubiquitin转移酶的系统,涉及Cap2和Cap3蛋白质来控制对细菌感染的先天免疫信号. 这种古老的机制启动循环GMP-AMP合成酶 (cGAS) 类核基转移酶 (CD-NTases) 的激活.

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