晚期艾滋病毒感染患者的Mpox:全球病例系列
Oriol Mitjà1, Andrea Alemany1, Michael Marks2
1Skin Neglected Tropical diseases and Sexually Transmitted Infections section, Fight Infectious Diseases Foundation, University Hospital Germans Trias i Pujol, Badalona, Spain.
Lancet (London, England)
|February 24, 2023
概括
在2022年的疫情中,Mpox对艾滋病毒感染者造成了不成比例的影响. 晚期艾滋病毒和低CD4计数 (<200细胞/毫米3) 与严重的mopox并发症和较高的死亡率有关,类似于艾滋病的定义条件.
科学领域:
- 传染性疾病
- 病毒学
- 免疫学
背景情况:
- 在2022年多国爆发期间,Mpox (麻疹) 对艾滋病毒感染者 (PLWH) 产生了重大影响.
- 虽然许多PLWH患者的临床结果与没有艾滋病毒的患者相似,但新出现的数据表明,晚期艾滋病毒患者的临床结果更差.
- 这项研究重点关注低CD4细胞计数 (<350细胞/ mm3) 的PLWH的临床特征和结果.
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