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Updated: Aug 8, 2025

Accessing Valuable Ligand Supports for Transition Metals: A Modified, Intermediate Scale Preparation of 1,2,3,4,5-Pentamethylcyclopentadiene
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Published on: March 20, 2017

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一种用于分子间 [4 + 2] 循环添加的无金属循环丁烯反应剂

Benjamin R Boswell1, Carl M F Mansson1, Gabrielle E Cabrera1

  • 1Department of Chemistry, Stanford University, Stanford, California 94305, United States.

Journal of the American Chemical Society
|March 1, 2023
PubMed
概括

一种新的无金属环丁试剂为化学合成提供了更安全和可扩展的替代品. 这一发现简化了复杂分子的制备,避免了危险的重金属副产品.

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Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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