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Updated: May 7, 2026

Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity
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大细胞的酸酶抑制mtRNA介导的干扰素的产生

Alexander Hooftman1, Christian G Peace2, Dylan G Ryan3,4,5

  • 1School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland. ahooftma@tcd.ie.

Nature
|March 8, 2023
PubMed
概括

巨细胞的新陈代谢包括阿斯巴酸-阿尔金酸分流. 抑制酸 (FH) 增加了炎症反应,突出显示了酸在巨细胞功能中的保护作用.

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