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Updated: Jul 25, 2026

A Method for Culturing Embryonic C. elegans Cells
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A Method for Culturing Embryonic C. elegans Cells

Published on: September 22, 2013

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在野生型C. elegans发育过程中死亡的细胞可以在ced-3突变体中充当神经元.

L Avery1, H R Horvitz

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge 02139.

Cell
|December 24, 1987
PubMed
概括

在C. elegans ced-3基因的突变防止细胞死亡,导致额外的细胞. 在突变分子中,相关细胞有时会弥补失去的神经元的损失.

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相关概念视频

Caspases01:24

Caspases

Caspase, a family of cysteine proteases, serve as effectors in apoptosis. The ced3 gene in C.elegans was first identified to be involved in apoptosis. This gene encodes the ced-3 caspase that is similar to the interleukin-1-beta converting enzyme or ICE in mammals. In addition to apoptosis, caspases also function in the inflammatory response. Inflammatory caspases are essential in activating pro-inflammatory cytokines that recruit immune cells and block the replication of pathogens inside cells.