在斑马的求爱歌曲中,体驱动着声音的发起
Felix W Moll1,2,3, Devorah Kranz1,2, Ariadna Corredera Asensio1,2
1NYU Neuroscience Institute and Department of Otolaryngology, New York University Langone Medical Center, New York, NY, USA.
Nature
|March 23, 2023
概括
通过激活特定的声音序列,
科学领域:
- 神经科学
- 行为生物学
- 听觉神经科学
背景情况:
- 远程输入对运动皮质电路中的动作执行具有重要影响.
- 胸膜投射塑造前运动活动,并可能为复杂的行为选择刻板印象的行为.
研究的目的:
- 在执行顺序运动时,研究乳头-运动皮层相互作用的机制.
- 确定胸膜输入在声序进展中的作用.
主要方法:
- 在斑马的HVC (正确名称) 曲核中的thalamic轴突的体内两光子成像.
- 在歌唱过程中对胸膜功能产生干扰.
- 在HVC中识别和描述thalamorecipient神经元的thalamic刺激.
主要成果:
- 甲状腺驱动器参与HVC前运动神经元的特定亚群 (~15%).
- 这些thalamorecipient神经元在音节开始之前是活跃的.
- 在音节的边界中切断歌曲.
结论:
- 语音输入对声动元素 (音节) 的进展至关重要.
- 泰拉木斯可以通过针对HVC中的特定"起始细胞"来启动歌曲组件.
- 运动性丘脑在序列行为中扮演皮质动态的导演角色.
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