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Updated: Aug 5, 2025

Chromatin Immunoprecipitation Assay Using Micrococcal Nucleases in Mammalian Cells
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在雄激素受体上通过胺介导的核活性促进转录

Julian Knerr1, Ralf Werner2,3, Carsten Schwan1

  • 1Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty, University of Freiburg, Freiburg, Germany.

Nature
|March 27, 2023
PubMed
概括

在DAAM2中发生突变会导致雄激素不敏感综合征. DAAM2与雄激素受体 (AR) 形成核转录滴,这对基因表达和前列腺癌细胞功能至关重要.

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