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在Polycomb抑制二维基因酶的H2AK119特异性的基础上

Weiran Ge1,2, Cong Yu1,2, Jingjing Li1,2

  • 1National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.

Nature
|March 29, 2023
PubMed
概括

聚合物抑制二维基因酶 (PR-DUB) 复合物精确地准了核细胞中的H2AK119ub1. 结构洞察力揭示了ASXL1和BAP1与DNA和基因组结合如何确保这种特定的基因调节机制.

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