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附录:农业化学品的协同作用增加了蜜蜂的死亡率

Harry Siviter1,2, Emily J Bailes3,4,5, Callum D Martin3

  • 1Department of Biological Sciences, Royal Holloway University of London, Egham, UK. Harry.Siviter.2016@live.rhul.ac.uk.

Nature
|April 24, 2023
PubMed
概括

No abstract available in PubMed .

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Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
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When drugs are administered, they can elicit either an agonist or antagonist effect on the body. Agonism occurs when a drug activates a specific receptor, triggering a biological response. On the other hand, antagonism happens when a drug binds to the same receptors but blocks their activation, thereby preventing a biological response.
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