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Updated: Jul 31, 2025

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在 κ-阿片类受体中的连接体和G蛋白选择性

Jianming Han1,2, Jingying Zhang3,4,5,6, Antonina L Nazarova7,8,9

  • 1Department of Anesthesiology, Washington University in St Louis, St Louis, MO, USA.

Nature
|May 3, 2023
PubMed
概括

κ-阿片类受体 (KOR) 是疼痛和上的目标, 但副作用是一个问题. 新结构揭示了KOR与不同G蛋白的相互作用,指导开发更安全的KOR向药物.

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