一个泛草转录组揭示了作物细胞分离的模式
Bruno Guillotin1,2, Ramin Rahni1, Michael Passalacqua3
1Center for Genomics and Systems Biology, New York University, New York, NY, USA.
Nature
|May 10, 2023
概括
通过比较三种草的根细胞转录组,可以发现特殊的细胞类型是如何进化的. 这项比较分析确定了保存的基因模块,并突出了基因组复制
科学领域:
- 植物生物学
- 基因组学
- 进化生物学
背景情况:
- 草被独立化,导致了不同的作物特征.
- 专门的细胞类型介绍了植物物种的关键特征.
研究的目的:
- 为了比较三个草种的根细胞转录组:Zea mays,Sorghum bicolor和Setaria viridis.
- 使用转录基因数据识别保存和分离的细胞类型和标记基因.
主要方法:
- 使用单细胞RNA测序 (scRNA-seq) 和单核RNA测序 (snRNA-seq).
- 从根细胞的转录数据进行了跨物种的比较分析.
- 发现了细胞类型的正义标记基因.
主要成果:
- scRNA-seq和snRNA-seq在单种动物中提供了互补的细胞识别读数.
- 对比分析显示了细胞类型之间的差异差异率,受基因模块招募的影响.
- 全基因组复制有助于快速进化的细胞类型的新基因表达域.
结论:
- 细度细胞分析可以识别物种中保存的功能模块.
- 了解细胞类型的进化,可以了解作物的关键功能.
- 比较转录组学有助于解读专门植物细胞的进化.
相关概念视频
Light Acquisition
8.5K
In order to produce glucose, plants need to capture sufficient light energy. Many modern plants have evolved leaves specialized for light acquisition. Leaves can be only millimeters in width or tens of meters wide, depending on the environment. Due to competition for sunlight, evolution has driven the evolution of increasingly larger leaves and taller plants, to avoid shading by their neighbors with contaminant elaboration of root architecture and mechanisms to transport water and nutrients.
8.5K
Transgenic Plants
7.3K
Recombinant DNA technology called transgenesis is often used to add a foreign gene or remove a detrimental gene from an organism. Such genetically modified organisms are called transgenic organisms.
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
The first-ever transgenic plant was a tobacco plant developed in 1983 that showed resistance against the tobacco mosaic virus. Since then, many transgenic plants have been developed and commercialized for improving the agricultural, ornamental, and horticultural value of a crop plant. Transgenic...
7.3K
Plant Breeding and Biotechnology
19.5K
Crop cultivation has a long history in human civilization, with records showing the cultivation of cereal plants beginning at around 8000 BC. This early plant breeding was developed primarily to provide a steady supply of food.
19.5K
Gene Evolution - Fast or Slow?
7.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
In contrast, regions which code...
7.2K
Evolutionary Relationships through Genome Comparisons
5.9K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.9K
Genome Size and the Evolution of New Genes
2.5K
2.5K


