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Updated: Jul 30, 2025

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小脆弱的新生儿 - 很大的影响潜力

Per Ashorn1, Ulla Ashorn2, Yvonne Muthiani2

  • 1Center for Child, Adolescent and Maternal Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; Department of Paediatrics, Tampere University Hospital, Tampere, Finland.

Lancet (London, England)
|May 11, 2023
PubMed
概括

预防幼弱新生儿 (SVN),定义为早产,怀孕年龄较小或出生体重较低的新生儿,对于减少新生儿死亡率和改善全球儿童生存率至关重要. 一个统一的定义和框架可以提高预防策略和结果.

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When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
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