自然两衍生宿主防御:具有潜在治疗价值的免疫调节剂
Jie Shi1, Jing Wu1, Guizhu Feng1
1Faculty of Basic Medical Sciences, Kunming Medical University, Kunming, Yunnan 650500, China.
Protein and peptide letters
|May 26, 2023
概括
两动物的宿主防御 (HDPs) 提供广泛的抗微生物和免疫调节功能. 本综述探讨了它们作为新型抗感染药物的潜力,以对抗日益增长的细菌耐药性.
科学领域:
- 免疫学和微生物学
- 自然产品化学 自然产品化学
背景情况:
- 细菌耐药性需要新的抗感染策略.
- 主体防御 (HDPs) 是跨王国发现的至关重要的先天性免疫分子.
- 两动物的皮肤是各种HDPs的丰富来源,具有强大的生物活性.
结论:
- 两类HDPs代表了开发新的抗感染疗法的有希望的途径.
- 克服临床开发挑战对于实现这些天然化合物的治疗潜力至关重要.
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