牙损是大脑内出血的危险因素
Elizabeth A LaValley1, Souvik Sen1, Emma Mason1
1Department of Neurology, University of South Carolina, School of Medicine, Columbia, South Carolina, USA.
Cerebrovascular diseases (Basel, Switzerland)
|May 26, 2023
概括
牙损显著增加了脑内出血 (ICH) 的风险. 这项研究发现,患有牙腐烂的人患上ICH的风险几乎是牙腐烂的四倍,这突显了潜在的公共卫生问题.
科学领域:
- 神经学 神经学
- 牙科 牙科是指牙科的专业.
- 公共卫生 公共卫生
背景情况:
- 牙损伤的原因是Streptococcus mutans,它具有一个原结合蛋白 (Cnm),并影响血小板聚合和矩阵金属蛋白酶-9的激活.
- 这种细菌与实验性脑内出血 (ICH) 的恶化有关,可能是ICH的危险因素.
研究的目的:
- 调查牙损伤的存在与脑内出血 (ICH) 的发生率之间的联系.
主要方法:
- 社区牙动脉样硬化风险研究 (DARIC) 对没有中风或ICH史的参与者评估了牙损伤和牙周病.
- 参与者被跟踪了10年,以记录发生的ICH事件.
- 根据牙科评估,使用考克斯回归分析计算ICH的原始和调整的危险比率 (HR).
主要成果:
- 在6315名受试者中,1338名 (27%) 患有牙损伤. 在10年内,ICH事件发生在7 (0.5%) 患有虫的人群和10 (0.2%) 没有虫的人群中.
- 与没有牙的人相比,患有牙的人更年轻,更有可能是男性,非洲裔美国人,高血压.
- 在牙损伤和ICH (原始HR2.69) 之间发现了显著的关联,在调整后加强了 (调整后HR3.88).
结论:
- 牙损成为发生脑内出血 (ICH) 的潜在危险因素.
- 需要进一步的研究来探索治疗牙损伤是否可以减轻ICH的风险.
相关概念视频
01:21Tooth Anatomy
583
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
583
01:26Arteries of the Head and Neck
1.5K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
1.5K
01:15Teeth
515
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
515