铁器时代耶路撒冷 (公元前7-6世纪) 的Giardia duodenalis和痢疾
Piers D Mitchell1, Tianyi Wang1, Ya'akov Billig2
1Department of Archaeology, University of Cambridge, Cambridge, UK.
Parasitology
|May 26, 2023
概括
古耶路撒冷所的沉积物揭示了Giardia duodenalis的存在,Giardia duodenalis是一种导致腹疾病的原生动物. 这一发现为古代近东地区这种感染提供了第一个微生物学证据.
科学领域:
- 古生物生物学 古生物生物学
- 古代近东历史 古代近东历史
- 寄生虫学的寄生虫学
背景情况:
- 铁器时代的耶路撒冷居民感染了肠道寄生虫,如鞭虫和圆虫.
- 引起痢疾的原生虫是脆弱的,并且很难通过光显微镜在古代样本中检测到.
研究的目的:
- 为了调查铁器时代耶路撒冷引起痢疾的原生动物的存在.
- 为了确定古代近东地区腹疾病的微生物证据.
主要方法:
- 来自两个铁器时代所 (公元前7世纪和公元前7世纪至6世纪初) 的沉积物样本的分析.
- 使用酶相关免疫吸收分析 (ELISA) 工具包检测*Entamoeba histolytica*,*Cryptosporidium* sp. 和*Giardia duodenalis*的抗原.
主要成果:
- 没有检测到 *Entamoeba* 和 *Cryptosporidium* 抗原.
- 在重复测试后,检测到Giardia duodenalis*抗原在两个所沉积物样本中.
- 这项研究提供了这种古老人口中*Giardia*感染的第一个微生物学证据.
结论:
- 在铁器时代的耶路撒冷出现了*Giardia duodenalis*,这表明与giardiasis相关的腹疾病.
- 古代美索不达米亚的医学文本表明,巨病爆发可能导致该地区的广泛疾病.
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