智能聚烯网格的机械性能:网格架构,等离子处理,热敏涂层和灭菌过程的影响
Sonia Lanzalaco1,2, Christine Weis3, Kamelia A Traeger3
1IMEM-BRT Group, Departament d'Enginyeria Química, EEBE, Universitat Politècnica de Catalunya, C/Eduard Maristany, 10-14, 08019 Barcelona, Spain.
ACS biomaterials science & engineering
|May 26, 2023
概括
用热敏水凝修改的智能聚烯隙网格显示出更好的机械阻力. 这种增强对于修复假肢至关重要,确保它们满足体内植入的要求.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
- 手术设备工程 手术设备工程
背景情况:
- 聚烯 (PP) 网用于手术修复.
- 检测手术感染和调节细胞附着是关键的挑战.
- 等离子处理和水凝接种可以改变网状特性.
研究的目的:
- 为了评估血处理和水凝移植PP Hernia Mesh的机械性能.
- 评估网格架构,水凝量和杀菌对机械性能的影响.
- 确定修改是否会影响适合进行修复.
主要方法:
- 通过等离子处理和聚-N-异烯胺 (PNIPAAm) 水凝移植对PP网格进行修改.
- 机械测试,包括破裂和线拉出测试在37°C.
- 对网状结构,水凝数量和乙烯氧化物灭菌效应的分析.
主要成果:
- 仅仅用等离子体治疗就减少了破裂和 suture 的拉出力.
- 接种的PNIPAAm水凝显著提高了网格的机械阻力.
- 乙烯氧化物灭菌没有对凝涂层网格的机械性能产生负面影响.
- 微图证实了水凝作为强化涂层在PP纤维上.
结论:
- 用PNIPAAm水凝修改PP网,可以提高机械性能.
- 改进的机械电阻满足了体内植入的要求.
- 这些智能网格为改善修复结果提供了潜力.
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