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Updated: Jul 29, 2025

Monitoring Dynamic Changes In Mitochondrial Calcium Levels During Apoptosis Using A Genetically Encoded Calcium Sensor
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通过光遗传工程 Ca2+ 振荡介导的 DRP1 激活促进了线粒体分裂和细胞死亡

Yi-Shyun Lai1, Cheng-Chi Chang1, Yong-Yi Chen1

  • 1Department of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan.

Journal of cell science
|May 26, 2023
PubMed
概括

光遗传控制的 (Ca2+) 振荡可以精确触发线粒体分裂,功能障碍和细胞死亡. 这种创新方法提供了对线粒体动态的时间控制,超过了传统的药理学方法.

关键词:
在 Ca2+ 振荡中.DRP1 DRP1 的使用方法线粒体裂变的线粒体裂变视觉遗传学 视觉遗传学

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