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在模两可的情况下,但不存在风险的决策障碍可能是慢性偏头痛患者药物过量使用的基础

Chi Ieong Lau^1,2,3,4,5, Wei-Hung Chen^1,6, Han-Cheng Wang^1,7

¹Dementia Center, Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.

|May 26, 2023

概括

患有慢性偏头痛加上药物过度使用头痛 (CM+MOH) 的患者在模两可的情况下表现出决策受损,这表明情绪反处理缺陷有助于MOH的发展.

科学领域:

神经科学是一个神经科学.
心理学心理学心理学
神经学神经学

背景情况:

慢性偏头痛 (CM) 患者药物过度使用头痛 (MOH) 的潜在因素尚未完全理解.
决策过程在MOH发展中的作用,特别是在不确定性 (模两可和风险) 的条件下,仍然存在争议.

研究的目的:

调查慢性偏头痛和药物过度使用头痛 (CM+MOH) 患者是否表现出决策方面的缺陷.
在CM+MOH患者中,区分模糊性与风险下的决策能力.

主要方法:

一项涉及75名参与者的横截面研究:25名CM+MOH,25名CM和25名健康对照 (HC).
使用爱荷华州博任务 (IGT) 评估了模两可的决策.
使用剑桥博任务 (CGT) 评估了处于风险中的决策,使用威斯康星卡排序测试 (WCST) 评估了执行功能.

主要成果:

与CM患者和HC患者相比,CM+MOH患者在IGT上表现出明显更不利的决策.
在CM+MOH患者,CM患者和HC患者之间没有发现CGT或WCST的显著差异.
在IGT上的表现与止痛药使用频率相反相关,这表明在模两可的情况下做出决策和MOH之间存在联系.

结论:

患有CM+MOH的患者表现出决策受损,特别是在模两可的情况下,而不是在危险的情况下.
这种分离表明,MOH的发病可能涉及被破坏的情绪反处理,而不是一般的执行功能障碍.

关键词:

剑桥博工作任务爱荷华州的博任务慢性偏头痛慢性偏头痛慢性偏头痛在决策过程中做出决定.药物过度使用头痛

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