液体栓塞剂用于内血管栓塞:一篇评论
Amrita Pal1, Jeffrey Blanzy1, Karime Jocelyn Rosas Gómez1
1Center for Interventional Biomaterials, School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ 85287, USA.
Gels (Basel, Switzerland)
|May 26, 2023
概括
液体栓塞剂被注射用于治疗血管异常,转化为固体植入物. 本综述涵盖了它们在血管内栓塞程序中的临床和临床前应用.
科学领域:
- 生物材料科学 生物材料科学
- 干预性放射学 干预性放射学
- 血管外科 血管外科
背景情况:
- 血管内栓塞 (EE) 是一种微创的技术,用于治疗血管异常,如动脉瘤和动脉静脉形 (AVM).
- 该程序涉及使用生物相容的栓塞剂通过导管在成像指导下输送异常血管的封闭.
研究的目的:
- 审查液体栓塞剂在内血管栓塞中的使用.
- 讨论它们在各种临床场景和临床前研究中的应用.
主要方法:
- 液体栓塞剂通过导管注入目标血管,使用X射线血管学.
- 这些药物通过聚合,沉或交联在现场固化.
- 天然和合成聚合物都被用作液体栓塞剂.
主要成果:
- 几种聚合物已成功开发用于液体栓塞剂.
- 液体栓塞剂为血管封闭提供了一种多功能方法.
结论:
- 液体栓塞剂是各种血管疾病的内血管栓塞的有效工具.
- 对聚合物开发和应用的持续研究提高了治疗选择.
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