在结构正常的心脏中,用于心室动的触发器和基质映射和切除
Simon Christie1, Sami Idris1, Richard G Bennett1
1Faculty of Medicine, Division of Cardiology, University of British Columbia, Gordon & Leslie Diamond Health Care Centre, 2775 Laurel St., 9th Floor, Vancouver, BC V5Z 1M9, Canada.
Journal of cardiovascular development and disease
|May 26, 2023
概括
由于心室动 (VF) 引起的突然心脏死亡 (SCD) 可以在没有心脏病的情况下发生. 导管切除为耐火性VF的高风险个体提供了一种新的治疗方法,针对触发物和基质.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 医疗器械 医疗器械
背景情况:
- 突发心脏病死亡 (SCD) 占美国心血管疾病死亡率的50%.
- 很大一部分SCD,特别是在年轻人中,在尸检上没有可识别的原因.
- 心室动 (VF) 是SCD中主要的终端节奏.
研究的目的:
- 对结构正常的心脏中VF的导管切除的当代方法进行审查.
- 专注于特定的疾病,包括异常性VF,短联结VF和J波综合征.
主要方法:
- 审查目前对虚拟货币机制的理解.
- 讨论针对VF触发物和基板的导管切除策略.
- 专注于针对特定条件的映射和废弃技术.
主要成果:
- 导管切除是一种有效的工具,用于管理耐火性VF.
- 在识别VF机制方面的进展有助于制定有针对性的废除策略.
- 了解延续VF的基质对于成功切除至关重要.
结论:
- 导管切除是耐火性VF患者的可行选择,特别是在没有结构性心脏病的情况下.
- 准VF触发物和基板可能会消除致命的失律症.
- 需要进一步的研究,但导管切除代表了重要的治疗进步.
相关概念视频
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
55
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
55
Disturbances in Heart Rhythm
1.0K
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
1.0K
Electrophysiology of Normal Cardiac Rhythm
6.6K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
6.6K
Dysrhythmias III: Characteristics of Dysrhythmias
13
Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per...
13
Mechanism of Cardiac Arrhythmias
972
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
972
Dysrhythmias VI: Management of Dysrhythmias
19
Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
19


