具有代谢综合征和没有代谢综合征的受试者之间的长期心率变异的差异:系统审查和元分析
Johan E Ortiz-Guzmán1, Sara Mollà-Casanova2, Óscar J Arias-Mutis3
1Department of Physiology, Universitat de València, 46010 Valencia, Spain.
代谢综合征 (MS) 显著降低了长期心率变化 (HRV) 的测量,包括SDNN,LF,VLF和TP. 这些发现突显了MS患者心脏自主功能障碍.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统功能 自主神经系统功能
- 代谢健康 代谢健康
背景情况:
- 代谢综合征 (MS) 与心血管风险增加有关.
- 心脏自主功能障碍是MS的潜在并发症.
- 心率变化 (HRV) 是自主功能的一个关键指标.
研究的目的:
- 量化综合MS对长期HRV的影响.
- 通过元分析来表征MS中的心脏自主功能障碍.
- 为了确定受MS影响的特定HRV参数.
主要方法:
- 原始研究的系统审查和元分析 (MA).
- 包括24小时HRV记录的研究,将多发性硬化症患者 (MS+) 与健康对照者 (MS-) 进行比较.
- 遵守PRISMA指导方针和进行PROSPERO注册 (CRD42022358975).
主要成果:
- 七项研究符合13篇定性综合文章中的MA标准.
- 在MS+患者中观察到SDNN,LF,VLF和TP的显著下降.
- 在rMSSD,HF或LF/HF比率中没有发现显著的修改.
结论:
- 长期HRV分析 (24h) 显示MS患者SDNN,LF,VLF和TP的持续减少.
- 具体的HRV参数 (rMSSD,HF,LF/HF比率) 没有显著改变.
- 由于有限的数据,非线性HRV分析是不确定的.
更多相关视频
09:40Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
Published on: January 19, 2017
10:31An Experimental Model of Diet-Induced Metabolic Syndrome in Rabbit: Methodological Considerations, Development, and Assessment
Published on: April 20, 2018
相关概念视频
Factors Influencing Heart Rate
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
Regulation of Heart Rates
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
Correlation between ECG and Cardiac Cycle
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
