系统性右心室和双心室生理学患者的长期随访:一个单一的中心体验
Cristina Ciuca1, Anna Balducci1, Emanuela Angeli2
1Pediatric Cardiology and Adult Congenital Heart Disease Program, Department of Cardio-Thoracic and Vascular Medicine, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Journal of cardiovascular development and disease
|May 26, 2023
概括
患有全身右心室 (SRV) 的成年人经常面临心律失常和心力衰竭等临床事件. 长期监测对于管理这些先天性心脏病病例至关重要.
科学领域:
- 心脏病学 心脏病学
- 成年人的先天性心脏病
- 心脏外科手术 心脏外科手术
背景情况:
- 在成年人中,先天性心脏病 (CHD) 的诊断越来越多.
- 与全身右心室 (SRV) 相关的CHD病例的预后较差.
- 了解SRV患者的长期结果至关重要.
研究的目的:
- 评估SRV.成年患者的长期临床结果和不良事件.
- 为了比较SRV不同病因之间的结果 (大动脉转移与先天纠正转移).
主要方法:
- 在2014-2020年期间评估的73名SRV患者的回顾性分析.
- 包括大动脉转移 (心房开关) 和先天纠正转移 (ccTGA) 的患者.
- 分析了临床事件,住院和生存的随访数据.
主要成果:
- 临床事件的高发病率,主要是心律失常 (27.1%) 和心力衰竭 (12.3%).
- 六年无事件生存率为90%;SRV组之间没有显著差异.
- 晚期加多增强 (LGE),较低的运动能力,较高的NYHA类,以及RV扩张/催眠预测较差的结果.
结论:
- 对SRV患者的长期随访有显著的临床事件,主要是心律失常和心力衰竭.
- 这些事件导致频繁的不定时住院.
- 尽管事件发生率很高,总体生存率仍然很高,但需要注意不良结果的风险因素.
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