固体器官移植接受者中可性菌病的诊断方法
Tirdad T Zangeneh1, Mohanad M Al-Obaidi1
1Division of Infectious Diseases, College of Medicine, University of Arizona, 1501 N Campbell Avenue, P.O. Box 245022, Tucson, AZ 85724, USA.
Journal of fungi (Basel, Switzerland)
|May 26, 2023
概括
在实体器官移植 (SOT) 接受者中诊断菌菌症是具有挑战性的. 本综述探讨了改善SOT患者早期检测和治疗这种真菌感染的诊断方法.
科学领域:
- 菌类学和传染病的研究
- 移植医学 移植医学 移植医学
- 诊断微生物学 诊断微生物学
背景情况:
- 型菌是一种特定区域内在的真菌感染,在大多数人中引起轻度疾病,但在免疫受损的个体中引起严重疾病.
- 固体器官移植 (SOT) 接受者面临严重菌菌病的高风险,需要及时诊断才能有效管理.
- 目前在SOT接受者中诊断菌菌的诊断方法往往在速度和准确性方面面临限制.
研究的目的:
- 审查和讨论当前的诊断模式,在SOT接收者的菌菌病.
- 突出在这个脆弱的患者群体中诊断菌菌症所带来的挑战.
- 探索改善诊断性能的策略,包括结合测试方法.
主要方法:
- 传统诊断技术的审查:培养,血清学和其他实验室测试.
- 评价分子诊断方法用于检测菌菌菌.
- 讨论特定于免疫功能受损的SOT接受者的诊断挑战.
主要成果:
- 常规和血清学测试存在限制,以及时和准确地诊断SOT接受者的菌菌病.
- 分子方法有可能提高诊断的灵敏度和速度.
- 早期诊断对于启动有效的抗真菌治疗和减少并发症至关重要.
结论:
- 提高诊断准确性和及时性对于在SOT接受者中管理菌菌症至关重要.
- 综合测试方法可以提高诊断方法的性能.
- 对优化诊断策略的进一步研究是有必要的,以改善临床结果.
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