眼球菌病:古老的和新的
Narges Maskan Bermudez1, Giselle Rodríguez-Tamez2, Sofia Perez1
1Dr. Philip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL 33125, USA.
Journal of fungi (Basel, Switzerland)
|May 26, 2023
概括
慢性指甲真菌感染 (Onychomycosis) 有限于口服治疗的成功. 本综述考察了针对指甲真菌感染的当前和新型口服疗法,以解决新兴药物耐药性的问题.
科学领域:
- 皮肤病学 皮肤病学
- 菌类学 菌类学是指菌类学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 甲状腺炎是一种常见的慢性真菌感染,影响着指甲板.
- 它导致指甲变色和变厚,影响生活质量.
- 目前的治疗方法面临着效率有限和耐药性发展的挑战.
研究的目的:
- 审查现有的口服治疗桃菌结核病的选择.
- 探索新兴的新型口服药物治疗指甲真菌感染.
- 为了解决桃菌病治疗中的特比纳耐药性问题.
主要方法:
- 对当前和试验性口服疗法的系统性文献综述.
- 对临床试验数据和耐药性模式的分析.
- 对药物的疗效,安全性和耐药性概况的评估.
主要成果:
- 特比纳芬和伊特拉可纳是经批准的口服治疗方法; 可纳是非标签使用的.
- 现有治疗方法的治愈率低于最佳水平.
- 全球对特尔比纳的耐药性越来越令人担忧.
结论:
- 目前治疗阴茎菌病的口服疗法在有效性上有局限性,并面临抗药性.
- 新型口服抗真菌剂显示出改善治疗结果的希望.
- 对新药的进一步研究对于有效地管理牛皮菌病至关重要.
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