绘制NETosis当前状态和新兴趋势的地图:一项文献计量研究
Hongqin Wang1, Xiaolin Liu1, Zijun Jia1,2
1Institute of Geriatric, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Medicine
|May 26, 2023
概括
中性细胞外细胞陷形成 (NETosis) 在免疫和自身免疫性疾病,癌症和COVID-19等疾病中至关重要. 研究正在迅速推进,重点是NETosis机制及其在各种病理中的作用.
科学领域:
- 免疫学 免疫学 免疫学
- 细胞生物学 细胞生物学
- 生物医学是生物医学.
背景情况:
- NETosis 是一个关键的中性粒细胞天生的免疫机制.
- 它对自身免疫性疾病,血栓形成,癌症和COVID-19的进展有显著的贡献.
- 图书统计分析为NETosis研究中的知识动态提供了客观的概述.
研究的目的:
- 对NETosis的文献进行定性和定量分析.
- 了解该领域的知识动态和研究趋势.
- 识别有影响力的国家,机构,作者和出版物.
主要方法:
- 从科学网络核心集合的文献的图书统计分析.
- 使用VOSviewer,CiteSpace和微软进行共同作者,共同发生和共同引用分析.
- 确定了顶级关键词和爆发检测趋势.
主要成果:
- 美国在NETosis研究方面处于领先地位;哈佛大学是最活跃的机构.
- 玛丽安娜·卡普兰和布林克曼五世是非常有影响力的作家.
- 主要期刊包括免疫学前沿,血液和自然医学.
- 新兴研究重点关注COVID-19和癌症,关键词如"细胞因子风暴"和"循环瘤细胞"显示强烈的爆发.
结论:
- NETosis研究正在经历显著的增长.
- 目前的重点是NETosis机制,天生的免疫力,自身免疫性疾病 (狼,类风湿性关节炎) 和血栓形成.
- 未来的研究将调查COVID-19中的NETosis和癌症转移.
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