中和透析中的氨损失:建模和实验
Anton Kozmai1, Mikhail Porozhnyy1, Violetta Gil1
1Membrane Institute, Kuban State University, 149, Stavropolskaya Str., 350040 Krasnodar, Russia.
Membranes
|May 26, 2023
概括
这项研究引入了一种新的数学模型,用于使用中和透析 (ND) 来分离氨 (Phe) 和NaCl. 该模型准确地预测了脱矿过程中的Phe损失,这对于优化分离过程至关重要.
科学领域:
- 化学工程是化学工程的重要组成部分.
- 分离科学 分离科学
- 数学建模的数学建模
背景情况:
- 氨基酸和盐分离在各种化学过程中至关重要.
- 中和透析 (ND) 提供了一种同时去矿化和氨基酸恢复的方法.
- 现有的模型没有全面考虑氨基酸原溶解和多种形式的运输.
研究的目的:
- 通过ND开发非稳定状态数学模型,通过ND分离氨酸 (Phe) 和NaCl.
- 为了考虑膜特性,溶液特性,以及所有Phe运输形式.
- 通过实验数据验证模型并分析Phe损失机制.
主要方法:
- 开发了一种非稳定状态的数学模型,其中包含了Phe原溶和多种形式的Phe运输的局部平衡.
- 在混合NaCl和Phe溶液上进行批量模式中和透析实验.
- 控制溶液的pH值,以尽量减少脱矿过程中的Phe损失.
- 通过比较模拟和实验的时间依赖导电性,pH和离子/Phe度来验证模型.
主要成果:
- 实验性去矿化达到90%,约有16%的Phe损失.
- 该模型准确地预测了导电性,pH和离子/Phe度的实验时间依赖性.
- 模拟表明,Phe损失的急剧增加超过了95%的去矿化.
- 达到99.9%的非矿物化可能会导致高达42%的Phe损失.
结论:
- 开发的数学模型有效地通过ND模拟了Phe和NaCl的分离.
- 该模型提供了对影响氨基酸损失的Phe运输机制的见解.
- 优化ND过程需要平衡脱矿率与可接受的Phe损失.
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