Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Applications Of NMR In Biology01:25

Applications Of NMR In Biology

3.8K
Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
3.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Novel and traditional anthropometric measures of obesity association with dynapenia in postmenopausal women.

Menopause (New York, N.Y.)·2026
Same author

Benchtop NMR as a clinical tool for acute respiratory illness: metabolic signatures associated with disease severity.

Respiratory research·2026
Same author

Higher endometrial thickness prior frozen embryo transfer is associated with lower first-trimester placental growth factor.

European journal of obstetrics, gynecology, and reproductive biology·2026
Same author

Pharmacokinetic analysis of nacubactam, a novel β-lactamase inhibitor, co-administered with meropenem in patients with a complicated urinary tract infection.

JAC-antimicrobial resistance·2026
Same author

Metabolic and endocrine factors involved in handgrip strength and dynapenia in postmenopausal women.

Maturitas·2026
Same author

A multi-center, open-label, two-part study to investigate the effect of renal function and hemodialysis on the pharmacokinetics of the novel β-lactamase inhibitor nacubactam.

Antimicrobial agents and chemotherapy·2026

相关实验视频

Updated: Jul 29, 2025

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
11:02

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

590

基板NMR基代谢学:生物医学应用的第一步.

Pilar Alonso-Moreno1, Ignacio Rodriguez1,2,3, Jose Luis Izquierdo-Garcia1,2,3

  • 1NMR and Imaging in Biomedicine Group, Instituto Pluridisciplinar, Universidad Complutense de Madrid, 28040 Madrid, Spain.

Metabolites
|May 26, 2023
PubMed
概括

基板核磁共振 (NMR) 为代谢学提供了具有成本效益的解决方案,使得在临床环境中能够发现疾病生物标志物. 这项技术对诊断和管理2型糖尿病和结核病等疾病充满希望.

关键词:
长板 长板 长板 长板生物标志物 生物标志物糖尿病 糖尿病患者 糖尿病患者诊断 诊断 诊断 诊断 诊断 诊断这是一个低地低地.代谢产物的代谢产物代谢生物组的代谢生物组核磁共振是一种核磁共振.结核病是一种肺结核病.

更多相关视频

Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy
07:54

Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy

Published on: December 15, 2011

13.2K
Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics
13:16

Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics

Published on: July 31, 2021

1.9K

相关实验视频

Last Updated: Jul 29, 2025

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
11:02

Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics

Published on: November 29, 2024

590
Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy
07:54

Assessing Hepatic Metabolic Changes During Progressive Colonization of Germ-free Mouse by 1H NMR Spectroscopy

Published on: December 15, 2011

13.2K
Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics
13:16

Pure Shift Nuclear Magnetic Resonance: a New Tool for Plant Metabolomics

Published on: July 31, 2021

1.9K

科学领域:

  • 生物化学 生物化学
  • 分析化学 分析化学
  • 临床诊断 临床诊断 临床诊断

背景情况:

  • 基于核磁共振 (NMR) 的代谢学对于疾病生物标志物识别至关重要.
  • 传统的NMR光谱仪的高成本和大尺寸限制了临床翻译.
  • 基板NMR提供了一个紧的,负担得起的替代方案,用于更广泛的临床采用.

研究的目的:

  • 审查目前在临床环境中对基板NMR的应用.
  • 突出基准NMR在疾病生物标志物发现和代谢分析中的潜力.
  • 评估常规临床使用的基板NMR的可行性.

主要方法:

  • 关于在代谢学中对基准NMR应用的现有文献的综述.
  • 分析表明基准NMR能够检测生物流体中的代谢物变化的能力的研究.
  • 对实验室NMR用于生物标志物检测的可复制性和准确性的评估.

主要成果:

  • 基板NMR成功检测了与2型糖尿病和结核病相关的代谢物水平变化.
  • 在尿液,血和唾液中使用基准NMR识别的代谢生物标志物.
  • 在检测与疾病相关的代谢变化方面证明了可重复性.

结论:

  • 基板NMR是临床代谢学的一个可行的,具有成本效益的工具.
  • 需要进一步的研究来优化协议并扩大生物标志物识别.
  • 基板NMR有可能彻底改变疾病诊断,预后和治疗监测.