评估在癌症幸存者的炼计划后,身体功能反应的个体水平变化
Heather J Leach1,2, Ciaran M Fairman3, Emma L Gomes4
1Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, 80523, USA. heather.leach@colostate.edu.
概括
癌症幸存者在运动后表现出各种身体功能改善. 像基线强度,年龄,BMI和出勤率这样的因素可以预测谁能从运动瘤学计划中获得有意义的好处.
科学领域:
- 运动瘤学运动瘤学
- 癌症康复康复 癌症康复
- 个性化医疗是个性化的医疗.
背景情况:
- 在癌症幸存者中建立了群体水平的身体功能反应.
- 个体反应的变化需要个性化炼方法.
- 了解异质性是优化运动干预措施的关键.
研究的目的:
- 评估癌症幸存者的身体功能反应的异质性.
- 确定与实现最小临床重要差异 (MCID) 相关的参与者特征.
- 使用来自成熟的癌症炼计划的数据.
主要方法:
- 评估握力,6分钟步行测试 (6MWT) 和坐到站前/后的3个月计划.
- 计算的个人变化得分和实现MCID的比例.
- 采用t测试,费舍尔的精确测试和决策树来分析MCID成就的预测因素.
主要成果:
- 250名参与者 (平均年龄55±14岁,69.2%是女性,84.1%是白人).
- 对于MCID的成就有所不同:握力为14.8%,6MWT为59%,坐立为63%.
- 基线握力,年龄,BMI和炼出席率预测了MCID的成就.
结论:
- 癌症幸存者的身体功能对运动的反应存在显著的变化.
- 确定了实现MCID的预测因素.
- 对生物,行为和遗传因素的进一步研究将完善个性化瘤运动.
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