在中老年澳大利亚人体构成的纵向变化和骨矿物质密度之间的关系
概括
保持或增加瘦肉量 (LM) 对于老年人骨健康至关重要. 这项研究发现,随着时间的推移,瘦肉质量的变化显著影响骨矿物质密度 (BMD) 的变化,而不是脂肪质量.
科学领域:
- 老年学是一门学科.
- 骨生理学 骨生理学
- 身体组成分析 身体成分分析
背景情况:
- 随着年龄的增长,关于身体组成和骨矿物质密度 (BMD) 变化的纵向数据有限.
- 了解这些关系对于制定减轻与年龄有关的骨质损失的策略至关重要.
研究的目的:
- 为了研究身体组成变化 (总体质量,肌肉质量,脂肪质量) 和老年成年人骨髓质量之间的纵向关联.
- 要确定是否瘦肉质量或脂肪质量是随着时间的推移BMD变化的更强的决定因素.
主要方法:
- 利用了3671名参与者 (年龄在46-70岁之间) 在布塞尔顿健康衰老研究中的数据.
- 在基线和大约6年后,使用双能X射线吸收计评估身体组成和BMD.
- 采用受限立方脊柱建模来分析总质量,瘦质量和脂肪质量的变化与部,大腿部和腰椎总体BMD变化之间的关系.
主要成果:
- 增加的总体质量与两个性别的部和大腿部的BMD积极相关,以及女性的脊椎.
- 瘦肉质量的变化与女性的所有测量部位以及男性的部和大腿部骨质量有积极的关联.
- 肌肉质量变化最高四分位数的女性与最低四分位数的女性相比,肌肉质量减少显著减少.
结论:
- 瘦肉质量变化是骨矿物质密度变化的一个更重要的决定因素,而不是6年时间内的脂肪质量变化.
- 保持或增加瘦肉质量与与年龄相关的骨质损失减少有关,强调其对老龄人口骨健康的重要性.
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