在65岁以上的人群中,脊椎压缩骨折后的生存率
Raquel Gutiérrez-González1,2, Ana Royuela3, Alvaro Zamarron4
1Department of Neurosurgery, Puerta de Hierro University Hospital, IDIPHISA, Manuel de Falla 1, 28222, Majadahonda, Madrid, Spain. rgutierrezgonzalez@yahoo.es.
Aging clinical and experimental research
|May 26, 2023
概括
患有脊椎压缩骨折 (VCF) 的老年患者的死亡率为36.2%,感染是主要的死亡原因. 年龄,男性性别和并发症显著增加死亡风险.
科学领域:
- 老年医学 老年医学
- 整形外科手术 整形外科手术
- 流行病学 流行病学
背景情况:
- 在65岁以上的患者中,脊椎压缩骨折 (VCF) 是一个重大的健康挑战.
- 与VCFs的保守管理相比,手术治疗 (脊椎增大) 的死亡率较低.
研究的目的:
- 分析被诊断患有VCF的老年患者 (65岁以上) 的整体存活率.
- 为了确定这一人口群体中死亡的主要原因.
- 确定与VCF后死亡风险增加相关的因素.
主要方法:
- 对492名65岁以上患有急性,非病理性胸部或腰部VCF的患者进行了回顾性分析 (2017年1月至2020年12月).
- 排除<2年随访或需要关节切除的患者.
- 使用了卡普兰-梅尔生存分析,日志等级测试和多变量考克斯回归.
主要成果:
- 平均随访时间为50.5个月后,总死亡率为36.2%.
- 在1,12,24,48,60个月的生存率分别为97.4%,86.6%,78.0%,64.4%和59.4%.
- 感染是死亡的主要原因;年龄,男性性别,瘤病史,非创伤性骨折机制和并发病是死亡的独立风险因素.
结论:
- 患有VCF的老年患者的整体死亡率相当高 (36.2%).
- 死亡率的关键独立预测因素包括晚年,男性性别,瘤病史,非创伤性骨折原因和住院并发症.
- 在脊椎增强和保守治疗组之间没有观察到生存曲线的显著差异.
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